Iron Quantification with LiverLab
نویسنده
چکیده
Multi-echo Dixon VIBE contained in LiverLab provides liver fat fraction values which are corrected for the effects of transversal relaxation. By doing this, it also provides a simultaneous estimation of that transversal relaxation time T2*, which is corrected for fat signal effects, herefafter called T2c*. The reciprocal value of this estimate, fat-corrected R2c* = 1/ T2c*, can be used, within limits, to assess liver iron concentration (LIC). This note provides some guidelines for doing that.
منابع مشابه
Hepatic Iron Quantification on 3 Tesla (3 T) Magnetic Resonance (MR): Technical Challenges and Solutions
MR has become a reliable and noninvasive method of hepatic iron quantification. Currently, most of the hepatic iron quantification is performed on 1.5 T MR, and the biopsy measurements have been paired with R 2 and R 2* values for 1.5 T MR. As the use of 3 T MR scanners is steadily increasing in clinical practice, it has become important to evaluate the practicality of calculating iron burden a...
متن کاملR2* for myocardial iron quantification at 3T CMR using an advanced shimming algorithm
Background Quantification of myocardial iron overload is critical for the management of patients with hemochromatosis. T2* relaxation time or its inverse R2*, are currently the noninvasive gold standard at 1.5T, as they strongly correlate with myocardial iron concentration, and are obtained using a fast single breath-hold ECG-gated multi-echo GRE sequence. However, due to high sensitivity to B0...
متن کاملA fully automatic algorithm for assessing T2* and its certainty value for accurate cardiac and liver iron load determination
Background Quantification of myocardial and liver iron load has become a mainstay of guiding therapy in thalassaemia patients. However, current quantification methods are user dependent for data-point exclusion before curve fitting, and do not report the T2* certainty. Recently, an automatic inline maximum likelihood estimate (MLE) method with k-space Rician noise correction was validated again...
متن کاملQuantification of liver fat in the presence of iron and iodine: an ex-vivo dual-energy CT study.
PURPOSE Iodinated contrast media (CM) and iron in the liver are known to hinder an accurate quantification of liver fat content (LFC) with single-energy computed tomography (SECT). The purpose of this study was to evaluate the feasibility and accuracy of dual-energy CT (DECT) for ex vivo quantification of LFC, in the presence of iron and CM, compared with SECT. MATERIALS AND METHODS Sixteen p...
متن کاملMyocardial iron quantification using modified Look-Locker inversion recovery (MOLLI) T1 mapping at 3 Tesla
Background Quantification of myocardial iron overload is critical for the management of patients with hemochromatosis. The effects of excess iron on T1 and T2* relaxation times correlate directly with tissue iron concentration. T2* became the clinical standard at 1.5T as it can be easily obtained in a fast one breath-hold ECG gated multi-echo GRE sequence. At 3T, however, T2* quantification can...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2016